Maps & Directions Close Window Enter your address here to get Driving Directions to Irvine Regional Hospital and Medical Center : Street: City: State: Zip: Contact Information: Irvine Regional Hospital and Medical Center 16200 Sand Canyon Avenue Irvine, CA  92618 949-753-2000 Use Subject to License/Copyright   This map is for informational purposes only. No representation is made or warranty given as to its content or usability. User assumes all risk of use. Tenet Healthcare, Google, and their suppliers assume no responsibility for any loss resulting from such use.